Nanoscience and nanotechnology are the study and application of extremely small things ( at the nanoscale, which is about 1 to 100 nanometers )and can be used across all the other science fields, such as chemistry, biology, physics, materials science, and engineering.Stem cell science in concert with nanotechnology has the potential to revolutionize tissue regeneration and healing outcomes. Nanotechnology allows the creation of biomaterials with unique and defined properties that mimic the extracellular matrix (ECM) in the tissue and present temporal and spatial cues to develop 3-D multi-scale complex tissue systems. This session will discuss more such applications.